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Yohimbine hydrochloride is a chemical substance with the chemical formula C21H27ClN2O3 and a molecular weight of 390.9. It is a white to milky crystalline powder with a slightly bitter taste. It is easily soluble in chloroform, methanol and ethanol, and slightly soluble in water. Yohimbine hydrochloride has a melting point of 288-290°C, a specific rotation of 99 o (c=1%, H2O), and a refractive index of 103° (C=1, H2O). It is sensitive to light and should be stored at room temperature away from light.
CAS:65-19- 0
Chemical formula:C21H27ClN2O3
Molecular weight:390.9
Yohimbine hydrochloride (molecular formula C21H26N2O3HCL, English Yohimbinehydrochloride) is also known as Weibizhi, Yohimbine hydrochloride, Yohimbine alkali, Comfort Lede tablets, Comfort Lede. It is a white to milky white fine powder with a slight fragrance, a bitter and slightly astringent taste, a melting point of 288?~290?, and is easily soluble in chloroform, methanol, ethanol, and slightly soluble in water. The plant source is the dry bark of the wild African plant Yohimbe (CorynanteYohimbe) or the extract of the bark of the West African plant Rubia Chemicalbook. The pharmacological effects are manifested as increasing sexual muscle tension, non-destructive urine inhibition, accelerating the body's energy metabolism, and increasing energy supply. Clinically, a single dose is used to treat various types of male impotence and sexual dysfunction. The mechanism of action is to selectively block the presynaptic a2 receptors, promote the release of norepinephrine, make the cavernous nerve endings release more norepinephrine, reduce the venous return of the penis, facilitate congestion and erection, and increase the secretion of sexual fluid. When used in small amounts, it can cause swelling of the perineum, stimulate the spinal erection center and cause sexual hyperfunction.
Function
Enhance sexual function
Yohimbine hydrochloride can improve blood flow in the corpus cavernosum of the penis and increase erectile function by blocking a2 receptors. It is often used as an adjuvant treatment for male sexual dysfunction.
Promote lipolysis
Yohimbine can prevent fat storage and enhance fatty acid release by inhibiting a2-adrenaline receptors. It is often used in weight loss products and sports supplements.
Improve mental state
As a central nervous system stimulant, Yohimbine hydrochloride can increase sympathetic nerve activity, help relieve fatigue, improve mood and improve concentration.
Treat hypotension
It can increase blood pressure by promoting vasoconstriction and is used as an adjuvant treatment for hypotension-related diseases.link:https://www.greenneeherb.com/herbal-extracts/yohimbine-hydrochloride-yohimbe-extract-98.html